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Total Synthesis of Himalensine A (J. Xu, 2019)
Himalensine A (1) is a member of the daphniphyllum alkaloids isolated in 2016 from Daphniphyllum ...
Total Synthesis of Cortistatin A (K. C. Nicolaou, 2009)
The total synthesis of cortistatin A (1, see Scheme 1) by the K. C. Nicolaou research group publi...
Total Synthesis of Cortistatin A (M. Shair, 2008)
In one of the early total syntheses of cortistatin A (1, see Figure 1) the research group of Matt...
Synthesis of Cortistatin A from Prednisone (P. Baran, 2008)
For the enantioselective synthesis of complex alkaloid cortistatin A (1), the research group of P...
First Total Synthesis of Daphnezomines A and B (C. Li, 2020)
Alkaloids from the plant genus Daphniphyllum are known for their complex structure and attracted ...
Enantioselective Total Synthesis of Batrachotoxinin A (T. Luo, 2020)
Batrachotoxinin A (1, see Figure 1) is an alkaloid with a steroidal skeleton. The batrachtoxinins...
First Total Synthesis of Granatumine A (T. R. Newhouse, 2019)
In this total synthesis the research group of Timothy Newhouse from Yale University (USA) describ...
First Total Synthesis of Scabrolide A (B. M. Stoltz, 2020)
In 2002 Sheu et al. isolated scabrolide A (1) and other natural products from Taiwanese soft cora...
Total Synthesis of Bactobolin A (J. Švenda, 2020)
Bactobolin A (1) is a complex polyketide firstly isolated in 1979 by S. Kondo et al. from bacteri...
Total Synthesis of Thebainone A (P. Metz, 2020)
Despite several total syntheses of opiates since the 50s, the construction of these complex alkal...
Bioinspired Total Synthesis of Brevianamide (A. Lawrence, 2020)
Although already isolated by Birch et al. in 1969, it took 50 years for the first total synthesis...
First Total Synthesis of Canataxpropellane (T. Gaich, 2020)
In their publication in Science (T. Gaich et al. Science, 2020, 367, 676) the research group of T...
First Asymmetric Total Synthesis of Waihoensene (Z. Yang, 2020)
Although isolated already in 1997, the complex diterpene waihoensene was firstly synthesized twen...
First Total Synthesis of Darwinolide (M. Christmann, 2018)
The diterpenoid darwinolide (1) is a promising candidate for antibiotic research due to his antib...
Total Synthesis of Dysoxylactam A (T. Ye, 2020)
In this publication from Tao Ye (叶涛) et al. from Peking University Shenzhen Graduate School (bas...
Total Synthesis of Pimara-15-endiol (T. Magauer, 2020)
One of the most interesting biosynthetic transformation is the cyclization of terpenoids to stero...
Total Synthesis of Archazolid F (D. Menche, 2019)
After the synthesis of archazolid A and B Menche et al. from the University Bonn published the sy...
Total Synthesis of Ajudazol A (D. Menche, 2020)
Ajudazol A (1) is a secondary metabolite of mycxobacterial origin which containing an isochromano...
First Total Synthesis of a Harziane Diterpenoid (E. Carreira, 2019)
The E. M. Carreira research group from the ETH Zürich (Swiss) recently published in Angewandte Ch...
Total Synthesis of Manginoid A (S. A. Snyder, 2021)
The terpenoid manginoid A (1, see Figure 1) is a polycyclic terpenoid bearing a spirocyclohexaned...