Recently Updated Pages
Total Synthesis of Talatisamine (M. Inoue, 2020)
Talatisamine (1, see Figure 1) is a highly oxidized hexacyclic alkaloid. Isolated already almost ...
Total Synthesis of Stephadiamine and Metaphanine (K. Nagasawa, 2021)
Stephadiamine (1, see Figure 1) and metaphanine (2) are two alkaloids with a hasubanan core struc...
Total Synthesis of Ritterazine B (S. Reisman, 2021)
Ritterazine B (1, Figure 1) is an alkaloid bearing a pyrazine core with two pseudodimeric sites. ...
Total Synthesis of Alterbrassicicene C (J. L. Wood, 2022)
Alterbrassicicene C (1) is a diterpenoid with an unusual tetracyclic core structure. John L. Wood...
Total Synthesis of racemic Phyllantidine by Ring Expansion (J. L. Wood, 2020)
Phyllantidine (1) is member of the Securinega alkaloids family named after their first isolation ...
First Total Synthesis of Kopsinitarine E (D. Ma, 2020)
Kopsinitarine E (1) is a polycyclic alkaloid isolated from Kopsia species. In the journal Angewan...
Total Synthesis of Himalensine A (J. Xu, 2019)
Himalensine A (1) is a member of the daphniphyllum alkaloids isolated in 2016 from Daphniphyllum ...
Total Synthesis of Cortistatin A (K. C. Nicolaou, 2009)
The total synthesis of cortistatin A (1, see Scheme 1) by the K. C. Nicolaou research group publi...
Total Synthesis of Cortistatin A (M. Shair, 2008)
In one of the early total syntheses of cortistatin A (1, see Figure 1) the research group of Matt...
Synthesis of Cortistatin A from Prednisone (P. Baran, 2008)
For the enantioselective synthesis of complex alkaloid cortistatin A (1), the research group of P...
First Total Synthesis of Daphnezomines A and B (C. Li, 2020)
Alkaloids from the plant genus Daphniphyllum are known for their complex structure and attracted ...
First Total Synthesis of Granatumine A (T. R. Newhouse, 2019)
In this total synthesis the research group of Timothy Newhouse from Yale University (USA) describ...
First Total Synthesis of Scabrolide A (B. M. Stoltz, 2020)
In 2002 Sheu et al. isolated scabrolide A (1) and other natural products from Taiwanese soft cora...
Total Synthesis of Bactobolin A (J. Švenda, 2020)
Bactobolin A (1) is a complex polyketide firstly isolated in 1979 by S. Kondo et al. from bacteri...
Total Synthesis of Thebainone A (P. Metz, 2020)
Despite several total syntheses of opiates since the 50s, the construction of these complex alkal...
Bioinspired Total Synthesis of Brevianamide (A. Lawrence, 2020)
Although already isolated by Birch et al. in 1969, it took 50 years for the first total synthesis...
First Total Synthesis of Canataxpropellane (T. Gaich, 2020)
In their publication in Science (T. Gaich et al. Science, 2020, 367, 676) the research group of T...
First Asymmetric Total Synthesis of Waihoensene (Z. Yang, 2020)
Although isolated already in 1997, the complex diterpene waihoensene was firstly synthesized twen...
First Total Synthesis of Darwinolide (M. Christmann, 2018)
The diterpenoid darwinolide (1) is a promising candidate for antibiotic research due to his antib...
Total Synthesis of Dysoxylactam A (T. Ye, 2020)
In this publication from Tao Ye (叶涛) et al. from Peking University Shenzhen Graduate School (bas...