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Total Synthesis of Cinnamodial and Dimerization to Capsicodendrin (S. Han, 2020)

Total Syntheses of Natural Products Terpenoids and Terpenes

The terpenoid capsicodendrin (1, Figure 1) is a dimer of cinnamodial (2) which was already isolat...

Updated 2 years ago by Stephan Scheeff

Total Synthesis of Gibberellin GA18 Methyl Ester (M. Dai, 2022)

Total Syntheses of Natural Products Terpenoids and Terpenes

Gibberellins are plant hormones that are synthesised in a variety of ways before. In the paper pu...

Updated 2 years ago by Stephan Scheeff

Structural Revision and Total Synthesis of ent-Halioxepine (M. Kalesse, 2021)

Total Syntheses of Natural Products Terpenoids and Terpenes

Halioxepine (1, see Figure 1) is a meroterpene isolated in 2011 by Junichi Tanaka and co-workers ...

Updated 2 years ago by Stephan Scheeff

Formal Total Synthesis of Atropurpuran (K. Tanino, 2020)

Total Syntheses of Natural Products Terpenoids and Terpenes

Atropurpuran (1) represents a complex diterpenoid featuring a pentacyclic skeleton. The research ...

Updated 2 years ago by Stephan Scheeff

First Total Synthesis of Cryptotrione (X.S. Peng, 2020)

Total Syntheses of Natural Products Terpenoids and Terpenes

Cryptotrione (1) is a complex terpenoid isolated in 2010. Now Xiao-Shui Peng (彭小水) and coworkers ...

Updated 2 years ago by Stephan Scheeff

First Total Synthesis of Glaucocalyxin A (Y. Jia, 2020)

Total Syntheses of Natural Products Terpenoids and Terpenes

Using a radical cyclization strategy at the very beginning of their synthesis, the Yanxing Jia (贾...

Updated 2 years ago by Stephan Scheeff

Total Synthesis of Bilobalide (R. Shenvi, 2019)

Total Syntheses of Natural Products Terpenoids and Terpenes

Bilobalide (1, see Figure 1) is a sesquiterpene which can be found in Gingko leaves and is relate...

Updated 2 years ago by Stephan Scheeff

Total Synthesis of Trihydroxytremulenone, Concenolide C and E by Pd-Cyclization (B. Trost, 2020)

Total Syntheses of Natural Products Terpenoids and Terpenes

Complex terpenoids like 10,11,12-trihydroxy tremulenone (1), cocenolide C (2) and E (3, Figure 1)...

Updated 2 years ago by Stephan Scheeff

Total Synthesis of Artemisinin (A. Giannis, 2018)

Total Syntheses of Natural Products Terpenoids and Terpenes

Artemisinin was discovered in the seventies by Tu Youyou (屠呦呦) and the unique structure of this t...

Updated 2 years ago by Stephan Scheeff

Total Synthesis of Pladienolide B (M. J. Krische, 2021)

Total Syntheses of Natural Products Polyketides

Pladienolide B (1, see Figure 1) is a polyketide bearing multiple stereogenic center. In a publis...

Updated 3 years ago by Stephan Scheeff

First Total Synthesis of Bufospirostenin A (C.-C. Li, 2020)

Total Syntheses of Natural Products Steroids

Bufospirostenin A (1, Figure 1)  is a bioactive steroid from the bile and venom of the toad Bufo ...

Updated 4 years ago by Stephan Scheeff

Total Synthesis of Olivil and related Lignans (S. Hanessian, 2020)

Total Syntheses of Natural Products Lignans

Despite reported for the first time over 200 years ago, the lignan olivil (1, see Figure 1) never...

Updated 4 years ago by Stephan Scheeff