Alkaloids

Enantioselective Total Synthesis of Batrachotoxinin A (T. Luo, 2020)

Batrachotoxinin A (1, see Figure 1) is an alkaloid with a steroidal skeleton. The batrachtoxinins...

Bioinspired Total Synthesis of Brevianamide (A. Lawrence, 2020)

Although already isolated by Birch et al. in 1969, it took 50 years for the first total synthesis...

First Total Synthesis of Daphnezomines A and B (C. Li, 2020)

Alkaloids from the plant genus Daphniphyllum are known for their complex structure and attracted ...

Synthesis of Cortistatin A from Prednisone (P. Baran, 2008)

For the enantioselective synthesis of complex alkaloid cortistatin A (1), the research group of P...

Total Synthesis of Cortistatin A (M. Shair, 2008)

In one of the early total syntheses of cortistatin A (1, see Figure 1) the research group of Matt...

Total Synthesis of Cortistatin A (K. C. Nicolaou, 2009)

The total synthesis of cortistatin A (1, see Scheme 1) by the K. C. Nicolaou research group publi...

First Total Synthesis of Granatumine A (T. R. Newhouse, 2019)

In this total synthesis the research group of Timothy Newhouse from Yale University (USA) describ...

Total Synthesis of Himalensine A (J. Xu, 2019)

Himalensine A (1) is a member of the daphniphyllum alkaloids isolated in 2016 from Daphniphyllum ...

First Total Synthesis of Kopsinitarine E (D. Ma, 2020)

Kopsinitarine E (1) is a polycyclic alkaloid isolated from Kopsia species. In the journal Angewan...

Total Synthesis of racemic Phyllantidine by Ring Expansion (J. L. Wood, 2020)

Phyllantidine (1) is member of the Securinega alkaloids family named after their first isolation ...

Total Synthesis of Talatisamine (M. Inoue, 2020)

Talatisamine (1, see Figure 1) is a highly oxidized hexacyclic alkaloid. Isolated already almost ...

Total Synthesis of Thebainone A (P. Metz, 2020)

Despite several total syntheses of opiates since the 50s, the construction of these complex alkal...

Total Synthesis of Tronocarpine (K. Namba, 2021)

Tronocarpine (1, see Figure 1) is a pentacyclic alkaloid isolated from the plant species Tabernae...