Lignans

Lignans are a widely distributed class of plant secondary metabolites biosynthesised through the oxidative coupling of two phenylpropanoid units. Found extensively in flaxseed, sesame, grains, and woody plants, they serve key roles in plant defense and exhibit significant antioxidant and biological activities.

Total Synthesis of Olivil and related Lignans (S. Hanessian, 2020)

Despite reported for the first time over 200 years ago, the lignan olivil (1, see Figure 1) never...

Enantioselective Total Synthesis of Batrachotoxinin A (T. Luo, 2020)

Bioinspired Total Synthesis of Brevianamide (A. Lawrence, 2020)

Total Synthesis of Heilonine from the Wieland–Miescher Ketone by Mingji Dai (JACS, 2024)

First Total Synthesis of Daphnezomines A and B (C. Li, 2020)

Synthesis of Cortistatin A from Prednisone (P. Baran, 2008)

Total Synthesis of Cortistatin A (M. Shair, 2008)

Total Synthesis of Cortistatin A (K. C. Nicolaou, 2009)

First Total Synthesis of Granatumine A (T. R. Newhouse, 2019)

Total Synthesis of Himalensine A (J. Xu, 2019)

First Total Synthesis of Kopsinitarine E (D. Ma, 2020)

Total Synthesis of racemic Phyllantidine by Ring Expansion (J. L. Wood, 2020)

Total Synthesis of Ritterazine B (S. Reisman, 2021)

First Total Synthesis of Stemocurtisine (M. Dai, 2026)

Total Synthesis of Stephadiamine and Metaphanine (K. Nagasawa, 2021)

Total Synthesis of Talatisamine (M. Inoue, 2020)

Total Synthesis of Thebainone A (P. Metz, 2020)

Total Synthesis of Tronocarpine (K. Namba, 2021)

Total Synthesis of Ajudazol A (D. Menche, 2020)

Total Synthesis and Structural Revision of Amphirionin-2 (H. Fuwa, 2021)

Total Synthesis of Archazolid F (D. Menche, 2019)

Total Synthesis of Bactobolin A (J. Švenda, 2020)

Total Synthesis of Dysoxylactam A (T. Ye, 2020)

Total Synthesis of Mycinolide IV and Aldgamycin N (A. Fürstner, 2021)

Total Synthesis of Pladienolide B (M. J. Krische, 2021)

First Total Synthesis and Structural Revision of Prorocentin (A. Fürstner, 2023)

Enantioselective Total Synthesis of Rubellin C (U. Tambar, 2020)

Total Synthesis of Salimabromide (Hai-Hua Lu, 2022)

First Total Synthesis of Tuscoron D and E (D. Menche, 2019)

First Total Synthesis of Bufospirostenin A (C.-C. Li, 2020)

Total Synthesis of Alterbrassicicene C (J. L. Wood, 2022)

Total Synthesis of Artemisinin (A. Giannis, 2018)

Formal Total Synthesis of Atropurpuran (K. Tanino, 2020)

Total Synthesis of Bilobalide (R. Shenvi, 2019)

First Total Synthesis of Canataxpropellane (T. Gaich, 2020)

Total Synthesis of Cinnamodial and Dimerization to Capsicodendrin (S. Han, 2020)

First Total Synthesis of Cryptotrione (X.S. Peng, 2020)

First Total Synthesis of Darwinolide (M. Christmann, 2018)

Total Synthesis of Gibberellin GA18 Methyl Ester (M. Dai, 2022)

Total Synthesis of Garryine (Y. Qin, 2023)

First Total Synthesis of Glaucocalyxin A (Y. Jia, 2020)

Structural Revision and Total Synthesis of ent-Halioxepine (M. Kalesse, 2021)

First Total Synthesis of a Harziane Diterpenoid (E. Carreira, 2019)

Total Synthesis of Manginoid A (S. A. Snyder, 2021)

Total Synthesis of Pimara-15-endiol (T. Magauer, 2020)

First Total Synthesis of Scabrolide A (B. M. Stoltz, 2020)

Total Synthesis of Trihydroxytremulenone, Concenolide C and E by Pd-Cyclization (B. Trost, 2020)

First Asymmetric Total Synthesis of Waihoensene (Z. Yang, 2020)

Total Synthesis of Pleurotin (Y. Q. Long 2024)

Total Synthesis of Olivil and related Lignans (S. Hanessian, 2020)

Lignans

Total Synthesis of Olivil and related Lignans (S. Hanessian, 2020)

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